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Custom Synthesis

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Custom Synthesis

Owing to our prowess in Custom Synthesis, we provide the following services:

  • Reverse engineering and custom synthesis of niche products and key raw materials
  • Synthesis of impurities and reference standards

Our committed team offers the following superior-quality, trustworthy, fast and cost-effective chemistry services to pharmaceutical, life-science, chemistry, and agro-chemical industries:

  • Analytical & purification services
  • Chemical consultancy

  • Chemical process research, development & validation
  • Synthetic organic chemistry

We persistently strive to provide the finest custom synthesis projects at the best contracted prices in terms of full-time equivalent (FTE). Our skilled and experienced team of organic chemists renders custom synthesis of any small molecule compound with precision, including:

  • Building blocks, starting materials, and intermediates
  • Drug-like screening compounds
  • Newer analogs and chemical entities for hit-to-lead (H2L) development
  • Derivatives of lead compounds
  • Accomplishment of known bio-active compounds with covalent warheads and other moieties
  • Target substrates, inhibitors and activators
  • Reference compounds and potential impurities or contaminants
  • Metabolites
  • Transition metal ligands

Our team is skillful in synthetic route scouting for your molecules due to the following advantages:

  • Building blocks, starting materials, and intermediates
  • Drug-like screening compounds
  • Newer analogs and chemical entities for hit-to-lead (H2L) development
  • Improvement of novel and customized synthetic routes through initial lab-scale research
  • Optimization and search of the best cost- and time- efficient synthetic route (e.g., higher yield, lower costs, lower environmental impact, reduction of by-products)
  • Alternative synthetic routes (e.g., avoiding hazardous starting materials, blind-alley or inappropriate synthesis methods, IP-protected compounds, etc.)

We offer a wide-range of early drug discovery services detailed below as an initiative of drug development projects:

  • Hit and lead optimization
  • Product scale-up
  • Reaction and process optimization
  • Catalyst screening and optimization

  • Peptidomimetics design, synthesis & characterization
  • Customizable quality assurance services
  • Characterization of physical and chemical properties
  • Analogue Search

In contract research and development, our focus is on client’s requirements pertaining to pioneering chemistry, unique products, time and cost considerations.

Custom synthesis request processing

We accomplish custom synthesis of individual compounds and screening libraries in flexible terms of contracted prices and FTE. Our R&D team meticulously evaluates the client’s projects with respect to project objectives, criteria and compound specifications provided by the client to describe a desired compound, such as:

  • Chemical name, structure or CAS number
  • Quantity needed
  • Purity and quality control requirements
  • Exclusivity and confidentiality preferences
  • Any other specific requirements

After evaluating the project, we send a quotation capturing the general and/or confidentiality terms to defend the client’s interests and intellectual property.